My lab is interested in understanding how the DNA damage response is regulated specifically at telomeric DNA.
Fifteen years ago, Aubrey de Grey organized the first SENS roundtable–Strategies for Engineering Negligible Senescence. It was a small group of out-of-the-box thinkers, heretics who talked about attacking head-on the idea that aging is just part of the human condition, looking for medical (and beyond-medical) treatments that would restore strength, stamina, and alertness, and lower the risk of all the diseases of old age at once.
Last month a team of doctors and scientists made the case to regulators at the Food and Drug Administration (FDA) to consider approving anti-aging drugs as a new pharmaceutical class. Such a designation would treat aging as disease rather than...