My lab is interested in understanding how the DNA damage response is regulated specifically at telomeric DNA.
Two recent studies, both published in the journal Nature Biotechnology, show a promising alternative to small-molecule drugs that are the mainstay of antibiotics today.
The DNA consists of two complementary strands. When one breaks, then repairing the other one is easy— the complementary strand is used as a guide. But when double-stranded breaks occur, proper repair is a complex problem.