Video Friday: Greg Fahy on Cryopreservation
Dr. Fahy will be appearing at the Alcor 2015 Conference in Scottsdale Arizona.
Dr. Gregory Fahy is the Vice President and Chief Scientific Officer of 21st Century Medicine, Inc. (21CM), a cryobiological biotechnology company focused on whole organ cryopreservation as well as on the cryopreservation of organized tissues. In 1981, he introduced the concept of organ vitrification, and in 1984, his first full paper on the subject was published, a paper that is now the most widely-cited paper ever published in the journal Cryobiology. In 1985, his paper in Nature with colleague W. F. Rall transformed the field of reproductive cryobiology by showing that embryos can survive vitrification in high proportions. In pursuit of the goal of whole organ banking, Dr. Fahy introduced many new concepts into the broader field of cryobiology, including cryoprotectant toxicity neutralization, qv* theory, designed ice interface dopants (“ice blockers”), the relevance of the Tg-Th intersection, chilling injury abrogation by tonicity adjustment, vitrification-catalyzed nucleation, viscosity-based storage time projections, the FlowLock perfusion technique, and many others. In 2009, he and his colleagues at 21CM published the first paper showing that a rabbit kidney can survive long-term after vitrification and transplantation and provide life support function, but with some ice damage. In 2013, he described how ice damage seen in the 2009 method can be eliminated without paying a toxicity penalty, and in 2015, he and colleague Brian Wowk discovered how to further reduce injury to mild levels. Dr. Fahy was elected as a Fellow of the Society for Cryobiology in 2014. A student also of the biology of aging, Dr. Fahy published The Future of Aging in 2010 and is currently organizing the first human trial of thymus regeneration.
In this video Dr. Fahy discusses the latest advances in the field of Cryonics, including vitrification and organ banking. Dr. Fahy has described the potential for organ banking to extend the human lifespan by eliminating up to one third of all human deaths. More information at http://manhattanbeachproject.com