Estrogen controls how the brain processes sound

This is Liisa Tremere, Jin Jeong, and Raphael Pinaud.Scientists at the University of Rochester have discovered that the hormone estrogen plays a pivotal role in how the brain processes sounds.

The findings, published in today’s issue of The Journal of Neuroscience, show for the first time that a sex hormone can directly affect auditory function, and point toward the possibility that estrogen controls other types of sensory processing as well. Understanding how estrogen changes the brain’s response to sound, say the authors, might open the door to new ways of treating hearing deficiencies.

"We’ve discovered estrogen doing something totally unexpected," says Raphael Pinaud, assistant professor of brain and cognitive sciences at the University of Rochester and lead author of the study. "We show that estrogen plays a central role in how the brain extracts and interprets auditory information. It does this on a scale of milliseconds in neurons, as opposed to days, months or even years in which estrogen is more commonly known to affect an organism."

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