H+ Magazine
Covering technological, scientific, and cultural trends that are changing–and will change–human beings in fundamental ways.

Archive for the ‘Bio’ Category

Editor's Blog

April 14, 2014

What if we could re-engineer humans for the harsh environment of planets like Mars?

February 10, 2014

This week, I report on three items from the biomedical literature:

1) Creating pluripotent stem cells may be much easier than we thought.

2) Direct evidence that cancer is not a function of a cell gone rogue, but rather a systemic disease, dependent on cellular environment and chemical context.

3) Nailing the coffin of the theory that aging comes from the accumulation of a lifetime of DNA damage.

February 3, 2014

Telomere biology has the potential to extend human life span, to dramatically lower rates of the great remaining killer diseases: heart disease, stroke, and Alzheimer’s. All three diseases increase exponentially with age, and their toll will be slashed as we we learn how to address the body’s aging clocks.

January 27, 2014

Eliminating mutational load might offer a shortcut to the Singularity.

January 23, 2014

Andrew Hessel, Autodesk Inc Bio/Nano Programmable Matter group; Natasha Vita-More, H+ Board Chair and transhuman pioneer; Dr. Seth 'Adventure', New Flesh Workshop; Lucas Dimoveo and Olivia Webb , Grindhouse Wetwares

January 1, 2014

‘Personhood beyond the human’: Reflections on a very important conference Steve Fuller   [The issues discussed here will be taken forward at my keynote address to the British Sociological Association in Leeds, in April 2014.]   On 6-8 December 2013, Yale University played host to one of the most interesting and, I believe, significant conferences […]

December 24, 2013

Humanity+ is scheduling its next conference for April 2014 in Silicon Valley!

December 12, 2013

"I'm pretty much messing around with DNA all day!"

Methods for engineering biology. Nina DiPrimio discusses tools for design and construction and plans for future projects. Presented by Counter Culture Labs, this video is designed as an accessible introduction for bio-maker spaces for the basic tools of synthetic biology. Future projects, such as rose scented e coli, are detailed in a how-to of genetic modification. The safety of genetic modification is also discussed.

December 5, 2013


November 19, 2013

My theme the last few weeks has been the signals that trigger the body’s self-destruction with age. The easiest to target are molecules that circulate in the blood. Last week, I covered a few that decrease in blood concentration as we age, and that cripple our defenses. This week, I’ll talk about signals that increase as we age, and that activate self-destruction. There are two principal mechanisms of active self-destruction: inflammation and apoptosis=cell suicide. Both mechanisms are important to the healthy functioning of the body. Inflammation is our first defense against invading pathogens. Apoptosis elimnates diseased and cancerous cells before they can become a problem. But in old age, both are co-opted for self-destruction. Healthy tissues in the body are destroyed by apoptosis, and inflammation leads to arterial damage and heart disease, DNA damage and cancer.

The blood signals, too, are have helpful roles earlier in life, but turn traitorous with age.

Ben Goertzel and Hugo de Garis
January 18th, 2011

Ben Goertzel converses with Hugo de Garis on his transhumanist argument for the reality of a Creator.

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