Video: International Summit on Human Gene Editing

summit image

A major component of the National Academy of Sciences and the National Academy of Medicine’s Human Gene-Editing Initiative is an international summit to take place December 1-3 in Washington, D.C. Co-hosted with the Chinese Academy of Sciences and the U.K.’s Royal Society, the summit will convene experts from around the world to discuss the scientific, ethical, and governance issues associated with human gene-editing research.

Watch the live webcast below!

International Summit on Human Gene Editing: A Global Discussion

Convened by:

Chinese Academy of Sciences The Royal Society
U.S. National Academy of Sciences U.S. National Academy of Medicine

National Academy of Sciences Building 2101 Constitution Avenue, N.W. Washington, D.C. 20418

December 1-3, 2015

Tuesday, 1 December 2015

Agenda

7:00 am

Registration/Continental Breakfast

8:00 am

Welcome and Introductions

Summit Committee Chair David Baltimore, California Institute of Technology

Congressman Bill Foster (D-11th District, Illinois)
John P. Holdren, White House Office of Science and Technology Policy

Representatives of the Convening Organizations:

Ralph J. Cicerone, U.S. National Academy of Sciences Victor J. Dzau, U.S. National Academy of Medicine Zhihong Xu, Chinese Academy of Sciences
John Skehel, The Royal Society

8:05 am

Opening Remarks

1

8:35 am

Context for Summit

Summit Planning Committee Chair David Baltimore, California Institute of Technology

8:45 am

Context Through Three Lenses: Scientific, Historical, Legal

Moderator: Speakers:

Moderator: Speakers:

Discussants:

Ismail Serageldin, The Library of Alexandria
Klaus Rajewsky, Max Delbrück Center for Molecular Medicine Daniel J. Kevles, New York University
Alta Charo, University of Wisconsin, Madison

Jennifer A. Doudna, University of California, Berkeley
Maria Jasin, Memorial Sloan Kettering Cancer Center
Emmanuelle Charpentier, Max Planck Institute of Infection Biology Jin-Soo Kim, Seoul National University / Institute for Basic Science Jonathan Weissman, University of California, San Francisco

J. Keith Joung, Massachusetts General Hospital and Harvard Medical School
Bill Skarnes, Wellcome Trust Sanger Institute
Feng Zhang, Broad Institute of Harvard and MIT

9:40 am

Scientific Background on Gene Editing Technologies

11:05 am

Comments from the Floor

11:30 am

Lunch

1:00 pm

Applications of Gene Editing Technology: Human Germline Modification

Moderator: Speakers:

Discussants:

Robin Lovell-Badge, The Francis Crick Institute Peter Braude, King’s College London
Kyle Orwig, University of Pittsburgh
George Q. Daley, Boston Children’s Hospital

George Church, Harvard Medical School
Azim Surani, Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge

2:30 pm

Comments from the Floor

2

3:00 pm

Break

3:30 pm

Societal Implications of Emerging Technologies

Moderator: Speakers:

Annelien L. Bredenoord, University Medical Center Utrecht John Harris, University of Manchester
Hille Haker, Loyola University Chicago
Marcy Darnovsky, Center for Genetics and Society

Sharon F. Terry, Genetic Alliance

Eric Lander, Broad Institute of Harvard and MIT

4:30 pm

Comments from the Floor

5:15 pm

Limits to Our Understanding

Speaker:

5:45 – 7:00 pm

Breakout Sessions

6:30

Reception

8:00 pm

Adjourn

3

International Summit on Human Gene Editing: A Global Discussion

Convened by:

Chinese Academy of Sciences The Royal Society
U.S. National Academy of Sciences U.S. National Academy of Medicine

National Academy of Sciences Building 2101 Constitution Avenue, N.W. Washington, D.C. 20418

December 1-3, 2015

Wednesday, 2 December 2015

Agenda

7:15 am

Registration/Continental Breakfast

8:15 am

Welcome

Summit Planning Committee Chair David Baltimore, California Institute of Technology

8:30 am

Applications of Gene Editing Technology: Basic Research

Moderator: Speakers:

Duanqing Pei, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Rudolf Jaenisch, Massachusetts Institute of Technology
Janet Rossant, The Hospital for Sick Children and the University of Toronto

Jinsong Li, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences

9:15 am

Comments from the Floor

4

9:45 am

Break

10:15 am

Applications of Gene Editing Technology: Somatic Cell Therapy

Moderator: Speakers:

Discussants:

Adrian Thrasher, University College London
Fyodor Urnov, Sangamo BioSciences
Matthew Porteus, Stanford University
Weizhi Ji, Kunming Institute of Zoology, Chinese Academy of Sciences

Chad Cowan, Harvard University
Marco Weinberg, The Scripps Research Institute

11:30 am

Comments from the Floor

12:00 pm

Lunch

1:30 pm

Governance at the Institutional and National Level

Moderator: Speakers:

Pilar N. Ossorio, University of Wisconsin, Madison, and Morgridge Institute for Research
Jonathan Kimmelman, McGill University
Barbara J. Evans, University of Houston Law Center

Zhihong Xu, Peking University Jennifer Merchant, Université Paris II

2:10 pm

Comments from the Floor

2:30 pm

Break

3:00 pm

Governance at the International Level

Moderator: Speakers:

Indira Nath, All India Institute of Medical Sciences
Gary Marchant, Arizona State University
Thomas Reiss, Fraunhofer Institute for Systems and Innovation Research
Philip Campbell, Nature

3:30 pm

Comments from the Floor

5

4:00 pm

Break

4:30 pm

International Perspectives

Moderator: Speakers:

Ernst-Ludwig Winnacker, Gene Center Munich, Ludwig-Maximilians University of Munich
Fola Esan, Nigerian Academy of Sciences (Nigeria)
Bärbel Friedrich, Leopoldina — the German National Academy of Sciences (Germany)

Pierre Jouannet, Université Paris Descartes (France)
Ephrat Levy-Lahad, Shaare Zedek Medical Center and Hebrew University of Jerusalem (Israel)
Keymanthri Moodley, Stellenbosch University (South Africa)
Staffan Normark, Karolinska Institute (Sweden)
K. Vijay Raghavan, Department of Biotechnology, Government of India (India)

5:45 pm

Breakout Sessions

7:00 pm

Adjourn

6

International Summit on Human Gene Editing: A Global Discussion

Convened by:

Chinese Academy of Sciences The Royal Society
U.S. National Academy of Sciences U.S. National Academy of Medicine

National Academy of Sciences Building 2101 Constitution Avenue, N.W. Washington, D.C. 20418

December 1-3, 2015

Thursday, 3 December 2015

Agenda

7:30 am

Registration/Continental Breakfast

8:30 am

Welcome

Summit Planning Committee Chair David Baltimore, California Institute of Technology

Moderator: Françoise Baylis, Dalhousie University Speakers: Tetsuya Ishii, Hokkaido University

Catherine Bliss, University of California, San Francisco Ruha Benjamin, Princeton University

8:40 am

Interrogating Equity

9:30 am

Comments from the Floor

10:15 am

Break

7

10:45 am

Governance, Regulation, and Control

Moderator: Hank Greely, Stanford University
Speakers: David Relman, Stanford University and VA Palo Alto Health Care System

Richard Gold, McGill University
Charis Thompson, University of California, Berkeley

11:30 am

Comments from the Floor

12:00 pm

Lunch

1:30 pm

Going Forward: Closing Thoughts

Summit Committee Chair David Baltimore, California Institute of Technology

3:00 pm

Adjourn

8