A breakthrough — published in the September 15 online edition of Nature — explains at last the mystery at the heart of the central dogma of molecular biology.
In 1958, climbing the double helix stairway to a Nobel Prize, Francis Crick explained (and elaborated in 1970) what we now call “The central dogma of molecular biology” that is the backbone of the theory of information in the nucleus of living cells. It states that information can’t be transferred back from protein to either protein or nucleic acid, because the normal flow of biological information has three steps: